Ukuqonda ukuba iincwadana ze-HPMC zikhulisa njani i-viscofity

Intshayelelo:
I-Hydroxypropyl Methylcelceltulose (HPMC) isetyenziswa ngokubanzi kumashishini ahlukeneyo, kubandakanya nolwakhiwo, amayeza kunye nokutya. Enye yezakhiwo eziphambili ze-HPMC kukukwazi kwabo ukwandisa i-viscofity, eyona nto ibalulekileyo ekusebenzeni kwabo kwizicelo ezahlukeneyo.

Ukuqonda i-HPMC:
Phambi kokuba ichaphazele njani indlela abanamaza e-HPMC, kubalulekile ukuba ndiqonde ukuba le i-HPMC kunye nepropathi yayo esisiseko. I-HPMC yi-selsulose i-syntheshed synthethed ukusuka kwi-seluplose, i-polymer yendalo efumaneka kwizityalo. Isetyenziswe ngokubanzi njenge-thi cokener, i-stabilizer, kunye ne-mulsifier ngenxa yokuqulunqa kwevidiyo I-HPMC ihlala ifumaneka kwifom yomgubo kwaye inokutshitshiswa ngokulula emanzini ukwenza isisombululo se-viscous.

Iindlela zokuphucula i-viscofity:
I-HPMChees Ebehevers yandisa i-viscofity ngeendlela ezininzi, kubandakanya i-hydration, iqabane, kunye ne-hydrogen.

Hydration:
Xa i-HPMC POLDER ichithwe emanzini, apho kungena khona iimolekyuli zamanzi kwaye kunxibelelana ne-hydrophilic hydroxypropy ye-hydroxypropy kunye namaqela e-HETYL akhona kwi-HPMC Chain. Le nkqubo ye-hydration ibangela ukuba iimolekyuli ze-HPMC zidumbe, ezikhokelela kwivolumu kunye nokubonisa isisombululo. Inqanaba lokuhamba-mbambano lixhomekeke kwizinto ezinje ngobunzima bemolekyuli kunye nokugxininiswa kwe-HPMC, kunye neemeko zokusingqongileyo njengokwemvelo njengamaqondo obushushu kunye ne-PH.

I-Actlement:
Iimolekyuli ze-HPMC ziimixokelelwane ezinde zinomgangatho ophezulu wokuguquguquka. Xa ichithwanga emanzini, ezi ntambo zibandakanyeka omnye komnye, zenza ubume benethiwekhi ezithintela ukuhamba kwesisombululo. Njengoko uxinzelelo lwe-HPMC, inani lezintsuba likwanda, kukhokelela kwi-viscofity ephezulu. Esi siphumo sokuthambeka sibhengezwe ngakumbi kumanqanaba aphezulu eemolekyuli ze-HPMC.

I-hydrogen bound:
HPMC molecules contain numerous hydroxyl groups (-OH) along their chain, which can form hydrogen bonds with water molecules and with each other. Le mibhobho ye-hydrogen ifaka igalelo kumdibaniso kunye nokuzinza kwenethiwekhi ye-HPMC, ukwandisa i-viscosity. Ukongeza, i-hydrogen bound phakathi kweemolekyuli ze-HPMC kunye nezinye izinto ekuqulunqweni komthendeleko, njengokufaka i-fillers okanye i-onsortives, inokuba nefuthe kwi-viscosity.

Izinto ezichaphazela i-viscofity:
Izinto ezininzi zinefuthe kwi-viscosives ye-HPMC, kubandakanya:

Ubunzima bemolekyuli:
Ubunzima be-MPMUC ye-HPMC buchaphazela kakhulu iipropathi zayo zokuphucula i-viscofity. I-rolecular ephezulu ye-rolecular ye-HPMC idla ngokwenza iinethiwekhi ezinamandla kunye neenethiwekhi ezibanzi, zikhokelela kwizisombululo ze-viscofity ephezulu.

Uxinzelelo:
Ukuxinezeleka kwe-HPMC ekuqulunqweni kwembeko kuchaphazela i-viscosity yesisombululo. Ngokubanzi, ukugxininiswa okuphezulu kwe-HPMC kukhokelela kwi-viscofity ephezulu ngenxa yokunyuka kwe-Polymer Portures kunye ne-Polyments.

Iqondo lokushisa:
Iqondo lobushushu linokuba nefuthe kumhlahla wokuhamba kunye nokuhamba kweemolekyuli ze-HPMC kwisisombululo. Ngokubanzi, amaqondo obushushu asezantsi anciphise inkqubo ye-hydration kwaye anciphise ukuhamba kweMoleri, okukhokelela kwi-viscofity ephezulu. Nangona kunjalo, amaqondo obushushu agqithisileyo anokuchaphazela nokuhluma kwe-HPMC kwaye atshintshe indlela yokuziphatha.

Ph:
I-PH yesisombululo inokuchaphazela imeko ye-IyorIs yamaqela e-HPMC MOLECULE, ngaloo ndlela ufumana unxibelelwano lwayo ngeemolekyuli zamanzi kunye nezinye izinto ekuthetheni. Utshintsho kwi-PH lunokuba nefuthe inqanaba lokuhlela kunye ne-hydrogen, ngenxa yoko ukutshintsha uVeksity.

Ukusetyenziswa kwee-HPMCE
I-HPMCEESS ABHESESES ABASEBENZI bafumana izicelo ezixhaphakileyo kumashishini ahlukeneyo ngenxa yokuphucula iipropathi zabo. Ezinye iindlela eziqhelekileyo zibandakanya:

Ulwakhiwo:
Kwizicelo zokwakha, iincwadana ze-HPMC zisetyenziswa njengezongezo kwisifo esekwe kwisamente, iiplaters, kunye neethayile zokuphucula ukusebenza, ukugcinwa kwamanzi, kunye namandla okuhambisa amanzi. Ukunyuka kwe-viscosity enyukayo kunceda ukukhusela ukungena nokutyibilika komntu okunamathela ngexesha lokufaka isicelo, ukuqinisekisa ukugubungela iyunifomu kunye nokunamathela okungcono.

Amayeza:
Kumachiza asemachiza, amaphiko e-HPMC asetyenziswa kwi-tayili yetafile, ukunqunyanyiswa, kunye neefom zokukhululwa kwe-dosage. Uhlobo lwe-HPMC Solutions udlala indima ebalulekileyo ekulawuleni amaxabiso okukhutshwa kweziyobisi, ukuthintela i-rightization yeziyobisi, kunye nokuphucula uzinzo lwefomu.

Ishishini lokutya:
Kwishishini lokutya, amaphiko e-HPMC asetyenziswa njengamanzi amakhulu, izilo zokuzinzisa, kunye no-Enulsisier kwiimveliso ezahlukeneyo ezinjengesosi, ukunxiba, kunye needessert. UVenkile weZisombululo ze-HPMC unceda ekuphuculeni ukuthungwa, umlomo, kunye nokuzinza kweshesi yeemveliso zokutya, ukuqinisekisa ukuba iimpawu ezisemgangathweni kunye neempawu zemvakalelo.

I-Hydroxypropyl Methylcelcelsulose (HPMC) Ii-adhenss zizinto ezivelelayo ezaziziswa ngokwabo ukwandisa i-viscosity yezisombululo. Ngokuqonda iindlela zokuphucula izinto zokundwendwela, kunye nezinto ezichaphazela uVeksisity, abavelisi banokulinganisa ukwenziwa kweemfuno ezizodwa ze-HPMC zokufezekisa iimfuno ezithile zesicelo ngokwakhiwa, ukutya, ukutya, kunye namanye amashishini. Njengoko imfuno yemfuno yokuSebenza ePhakamileyo iyaqhubeka ikhula, i-HPMC ihlala ixabiseke kakhulu kwiipropathi zayo zokuguqula izinto kunye nezicelo ezichaphazelekayo.