Isishwankathelo se-hydroxypropyl methylcelcelgalose hpmc proceties

I-HydroxyPOpyl Methyl Selelose HPMC luhlobo lwe-ionic selsulose exutywe, eyahlukileyo kwi-Ionic Methyl Carboydymymethyl sether ixutywe ngayo. Ngenxa yomyinge ohlukileyo we-APENSGSYL Umxholo weHydroxypropy, ukusebenza kwayo kufutshane ne-hydroxypropyl methylcelcelceluplose. Nangona kunjalo, kwiindidi ezahlukeneyo, nangona kuphela iQela elincinci le-hydropyPlPOpy okanye inani elincinci leqela le-AFCICY liqulathwe, i-solity yeqela lezinto eziphilayo okanye iqondo lobushushu kwisisombululo esinamandla lahluke kakhulu.

1. Umoya wokuzithoba kwe-hydroxypropyl methylcelcelce
Ulwimi lwe-Hydroxypropyl Methyl Selelise in Asseleppropyl Methyl I-Methyl Selsulose iguqulwe yi-propylene oxide (ngoko ke inepropathi efanayo ne-methyl seluplose. I-seluplose iyafana nokuluka kwamanzi kubandayo kunye nokubethwa kwamanzi ashushu. Nangona kunjalo, ngenxa yeqela eliguqulweyo ye-hydroxypropy, ubushushu bayo bokuhlutha kumanzi ashushu bungaphezulu kakhulu kune-methyl seluplose. Umzekelo, i-viscosity yesisombululo se-hydroxypropyl methylcelcelcelose ene-2% yomxholo we-DS = 0.73 kunye ne-HydroxyPOpy I-MS = 0.46 yi-500 MPA's nge-20 ° C. Iqondo lokushisa layo lejeli elinokuthi lisondele kwi-100 ° C, ngelixa i-methylcelculose kwiqondo lobushushu i-55 kuphela malunga ne-55 ° C. Ngokuphathelele ukubenzela amanzi, kuye kwaphuculwa kakhulu. Umzekelo, i-hydroxypropyl ye-hydylcelcelcelsulose (i-Granular ye-0.2 ~ 0.5mm nge-20% isisombululo se-4% esinokusetyenziswa ngamandla egumbi, inyibilika ngokulula emanzini ngaphandle kokupholisa.

I-solungulity ye-hydroxypropyl methyl seluplose kwi-solling ye-soubing ye-shotyl ye-metyl ye-metyl ye-withyl ilunge kakhulu kwimveliso engasentla kwemveliso engentla kwemveliso engezantsi I-methylcelculose equkethe i-hydroxypropyl Nks = 1.5 ~ 1.8 kunye ne-APUSGY DS = 0.2 ~ I-SPOLS SOLLY SINGENCY THHADDARD NOPHANDO OLUFANELEKILEYO, I-TROFICT kunye ne-thermoplastic kunye ne-thermoplastic kunye ne-thermoplastic. Ikwanyibilika kwii-hydrocarble ezihlangwini ezinjengeDichloromethane kunye ne-chloroform, kunye nezinyibilikisi zendalo ezinje nge-acetone, i-Iyopropanol yotywala. Ukuqina kwayo kwizinyibilikisi zendalo kungcono kunokunyibilika kwamanzi.

I-2. IZINTO EKUFUMANELEKILEYO KAKUHLE ZOBUCHULE
Ukuphembelela izinto ze-Hydropyl Goutyl Secofity I-villasity ye-Hydroxyl I-Mythyl Sethyl Seleulose, njengozinye i-2% ye-2 ° C. Uhlobo lwemveliso olufanayo luyanda ngokunyusa uxinzelelo. Ngeemveliso ezinamatye ahlukeneyo eemolekyuli kugxininiso olufanayo, iimveliso ezinamatye amakhulu eemolekyuli zine-viscofity ephezulu. Ulwalamano lwayo ngamaqondo obushushu luyafana ne-methyl seluplose. Xa iqondo lobushushu liyanda, i-viscosity iqala ukuncipha, kodwa xa ifikelela kubushushu obuthile, i-viscosity yeqhinga inyuka ngequbuliso kwaye ukumela. Iqondo lokushisa le-gel lemveliso ye-viscofity ephezulu. iphakamile. Inqaku layo lejeli alihambelani kuphela nohlobo lwe-ether, kodwa nakumyinge we-wippoxy kunye ne-hydroxypropy kwi-ether kunye nenqanaba elipheleleyo. Kuya kufuneka iqatshelwe ukuba i-hydroxypropyl methylcelcelcelostistice kwaye isisombululo sayo sizinzile kubushushu begumbi ngaphandle kokupheliswa kwe-viszmatic.

3. Hydroxyl I-MethylcelceLcelose Acid kunye neAlkali Ukunganyangeki
Hydroxypropyl methylcelcelsele acid nolkali i-hydroxypropyl methylcelcelcelcelcelcelse i-acid kunye ne-alkali, kwaye ayichaphazelekanga kuluhlu lwe-pH 2 ~ 12. Inokumelana nenani elithile le-acid ukukhanya. Enje nge-forcid acid, i-acetic acid, i-ciccic acid, phosccinic acid, i-phoschoric acid, i-photoric acid, i-raric acid, njl njl I-Alkali efana neSoda ye-Caustic, i-Caustic Potsesh kunye namanzi e-lime ayinampembelelo kuyo, kodwa iya kwandisa nje i-viscomonity yesisombululo, kwaye emva koko kuya kubakho into ehamba kancinci kwikamva.

4. Ukuxutywa kwe-hydroxypropyl methylcelcelcelose
Ukungasebenzi kakuhle kwe-Hydroxypropyl Methyl I-Soutyropyl Methyl Isisombululo seSelinglese sinokudityaniswa ne-polymer polymer ye-prolymer kunye ne-vispared nge-viscofity ephezulu. Ezi pollements ezihlanganisiweyo zibandakanya i-polyethylene glycol, polyvinyl acetate, polysiloxion, polymethyl vinyl siloxane seloxane, i-hydroxyythy seluplose. I-Polymer yeNdalo efana ne-Gum Arabic, i-Bian Bean Gum, iKaraya Gum, njl njl. I-Hydroxypropyl Methylcelcelsulose inokuxutywa ne-mannitol okanye i-sorbilil esters ye-stearic acid okanye i-palmic acid, kwaye inokuxutywa ne-glycerin, i-shorbil kunye ne-mannitol. Ezi vili zinokusetyenziswa njenge-hydroxypropyl methylcelceluplose. Iplastiki esekwe kwiselfowuni.

I-5. Unxuwa kunye ne-Unity yangaphantsi kwe-hydroxypropyl methylcelcelcelgalose
I-Insulobil-inyibilikisi eselula-inyibilikisi ye-Hydroxypropyl Methylcelcelsulose inokuba yindawo enqamlezileyo enama-AldeyeyDes, kwaye ezi zinto zixineneyo zamanzi zichazekile kwisisombululo kwaye zinganyibiliki emanzini. I-AldehyDes eyenza i-Hydroxypropyl methylcelcelgalose iquka i-forlinehyde, i-Glycoxal, i-suminaldehyde, i-adipaldehyde, i-GOLDE kufuneka ihlawulwe kwixabiso lesisombululo. Ke ngoko, i-Gllyoxal ihlala isetyenziswa njenge-arhente enqamlezileyo kwimveliso yemizi-mveliso. Umthamo wolu hlobo lwe-arhente enqamlezileyo kwisisombululo yi-0.2% ye-10% ye-Ether Mass, ngokukhethekileyo i-7% ~ i-6% ye-6% yeyona ilungele i-glyngoxal. Iqondo lobushushu ngokubanzi lingu-0 ~, kwaye ixesha ngu-1 ~ 120min. Ukunxibelelanisa ukuphendula okugqogqa kudinga ukwenziwa phantsi kweemeko ze-acidic. Ngokubanzi, i-Inorganic eyomeleleyo ye-acid okanye i-orboxyylic acid yongezwa kwisisombululo sokulungelelanisa i-PH yesisombululo malunga ne-2 ~ 6, emva koko i-Aldelweni yongezwa ukuze isebenze ngokudibeneyo. . Ii-Acids zisetyenzisiwe zibandakanya i-hydrochloric acid, i-phosfuric acid, i-forchoric acid, i-acetic acid, i-succcinic acid, kwaye i-acid ye-ficki ifanelekile, kwaye i-acid ye-ficki ifanelekile. I-acid kunye ne-Aldehyde nazo zongezwe ngaxeshanye ukuvumela isisombululo se-nqamle kwi-PH yoluhlu olufunwayo. Le mpendulo idla ngokusetyenziswa kwinkqubo yokugqibela yonyango kwinkqubo yokulungiselela ye-seluplose. Emva kokuba i-Ether Sether itywiniwe, ilungele ukuhlamba kwaye ihlambulule ngamanzi nge-20 ° 8 ° C. Xa imveliso isetyenziswa, into eninzi into inokongezwa kwisisombululo semveliso ukuze ilungelelanise i-PH yesisombululo ukuba i-alkaline, kwaye imveliso iya kunyibilika kwisisombululo ngokukhawuleza. Le ndlela ikwasebenza nakwisisombululo se-selsulose esenziwe kwifilimu kwaye emva koko ifilimu iqhubekile ukuba iyenza ifilimu engenanto.

I-6. I-HydroxdPOpyl Methylcelcelcelose ichasa i-enzymes
I-HydroxyPOpyl Methylcelcelose ichasa i-enzymes. Kwithiyori, i-SeleXose Derivetives, enjengeqela ngalinye le-anyDroglucose, lineqela elibi lokufaka endaweni ye-enzymes, kodwa oko kuthetha ukuba i-enzymes egqithayo kwi-Cleulose Chain ayifani, kwaye i-microorganisms inokwenzeka I-Erode kufutshane ne-AnhydroglupClucose yokutsala iswekile. , ethatyathwa njengezondlo kwi-microorganisms. Ke ngoko, ukuba isidanga sokufakelwa kwe-Elessist seSeluplose yonyuka, ukuchasana nokuncwina kwe-erzymatic ye-Eler Selese ikwaphuculwe. Kuxelwe ukuba i-viscofity yentsalela ye-Hydroxypropyl Methylcelgalose (DS = 1.9) yi-7.3%, i-MTYLCELCELXELXOse (DSylcellulose (DSY = 1.7%, kunye ne-hydroxyythy yi-1.7%. Ingabonwa ukuba amandla a-enti-enzyme ye-hydroxypropy ye-methylcelcelcelcelcelgalose yomelele. Ke ngoko, i-enzyme egqwesileyo ye-hydroxypropyl methylceltulose, edityanisiweyo kunye neepropathi zayo ezilungileyo nefilimu, isetyenziswa ngokubanzi kwi-ortings-emulsion, njalo. Nangona kunjalo, kwisigqibo sexesha elide sesisombululo okanye ungcoliseko lwehlabathi ngaphandle, izinto ezigciniweyo zinokongezwa njengezilumkiso, kwaye ukhetho lungagqitywa ngokweemfuno zokugqibela zesisombululo. I-phenylmercuric acetate kunye ne-manganese fluorosilicicial zizinto ezisebenzayo, kodwa zinetyhefu, ingqalelo kufuneka ihlawulwe ngokusebenza, kwaye umthamo kufuneka uhlawulwe i-1 ~ 5mg ye-phenylmercuete ngelitha nganye yesisombululo.

I-7. Iipropathi ze-hydroxypropyl methylcelcelcelse
Ukusebenza kwe-HydroxyPOpyl Methylcelcelsey Ifilimu ye-Hydroxylypropyl Methylcelcel Inemifanekiso ebalaseleyo yefilimu, kwaye isisombululo se-ofisi ye-orvant sidityaniswe kwipleyiti yeglasi, kwaye singabonakali. Kunye nefilimu enzima. Inokuthini ukunyangwa okuhle nokunganyangeki kubushushu obuphezulu. Umzekelo, ukongeza iplastiki ye-hygroscopic inokuphucula i-slongtion kunye nokuguquguquka. Ukuphucula ukuguquguquka, iiplasitizeli ezinje nge-glyrin kunye ne-sorebil zilungele kakhulu. Ugxininiso lwesisombululo se-2% ~ 3%, kunye nexabiso leplastiki liyi-10% ~ 20% ye-seluplose ether. Ukuba umxholo weplastiki uphezulu kakhulu, i-shrinkagety ye-shrinknon ye-colloid yokuphelelwa ngumzimba iya kwenzeka phantsi komswakama okuphezulu. Amandla e-sunsed yefilimu eneplastiki eyongezwe inkulu kakhulu kunelo ngaphandle kweplastiki, kwaye iyakonyuka ngokunyuka kwenani elongeziweyo. Ngokuphathelele i-hygroscoficity yefilimu, isonyuka ngokunyuka kwexabiso leplastiki.