Ukudibanisa njani i-hydroxyproplol methylceltulose?

I-HydroxyPOpyl Methylcelcelsele (i-HPMC) isetyenziswa rhoqo ekwakhiweni, amayeza, ukutya namanye amasimi. Inesimo esihle, ukwenza ifilimu, ukuzinzisa kunye nokulungisa iipropathi. Indlela yokudibanisa echanekileyo ibalulekile ukuqinisekisa ukusebenza kwalo kunye nomgangatho wemveliso.

1. Ukulungiselela
Ukulungiselela izinto: Qinisekisa ukuba usebenzisa umgubo we-HPMC oMkhulu we-HPMC. Khetha i-viscofity efanelekileyo kunye neenkcazo ngokwesicelo esithile.
Ukulungiswa kwezixhobo: Umxube wesantya esiphezulu, abasasazi okanye umxube oqhelekileyo uhlala esetyenziswa. Izixhobo kufuneka zicoceke kwaye zikhululeke ungcoliseko.
Ukukhethwa kweSolvent: I-HPMC ihlala inyibiliza emanzini abandayo, kodwa izinyibilikisi zezinto eziphilayo okanye ezinye iindaba nazo zinokusetyenziswa kwezinye iimeko. Ukukhetha isinyibilikisi esifanelekileyo kubalulekile kumxube wokuxuba kunye nokusebenza kwemveliso yokugqibela.

2. Ukudibanisa amanyathelo
I-PARYRY: I-HPMC POMDER kufuneka ihlolwe kwangaphambili ukuze isuswe i-phumela kunye nokungcola ukuqinisekisa ukusasazeka.

I-Solvent Yongeza:
Indlela yokusasazwa kwamanzi ebandayo: Thula inani elifunekayo lamanzi abandayo kumxube, qala ukufunxa, kwaye kancinci uyongeze i-HPMC POMDER. Kulumkele ukongeza kakhulu ngexesha elinye ukuthintela ukwahluka. Qhubeka nokuxhokonxa de umgubo usasazeke ngokupheleleyo.
Indlela eshushu yokusasaza kwamanzi: Hlanganisa i-HPMC yomgubo wamanzi abandayo ukwenza ukunqunyanyiswa, kwaye emva koko uthulule emanzini ashushu afudumele ibe ngama-70-90 ° C. Shuma ngesantya esiphezulu sokunyibilikisa, emva koko wongeza amanzi abandayo ukuze uphole kubushushu begumbi ukufumana isisombululo sokugqibela.

Ukuchithwa kunye nokutyibilika:
Xa i-HPMC inyibilikisiwe emanzini, ukumiswa kwaqala kwaqala. Njengoko ixesha elitshatileyo lisonyuka kwaye iqondo lobushushu liyancipha, i-viscofity ngokuthe ngcembe yanda de ichithwe ngokupheleleyo. Ixesha lokutshabalalisa lidla ngokuthatha imizuzu engama-30 ukuya kwiiyure ezininzi, kuxhomekeka kwi-viscofity kunye ne-HPMC.
Ukuqinisekisa ukuchithwa okugqibeleleyo, isisombululo sinokuvunyelwa ukuba sime ixesha elithile (njengokulala) ukufezekisa i-viscofity efanelekileyo.

Uhlengahlengiso kunye nohlengahlengiso:

Ukuba kukho imfuneko, iipropathi zesisombululo zingahlengahlengiswa ngokongeza ezinye izithako (ezinje ngeendawo zokugcina, iicuba, njl njl). Ukongezwa kufuneka kwenziwe ngokuthe ngcembe kwaye kuqinisekiswe ukusasazwa kweyunifomu.
Ukupholisa kunye nokudaya:

Ukususa amasuntswana anqatyisiweyo kunye neebhubhu zomoya, isihluzo okanye isigatya sinokusetyenziswa. Ukuqulunqa kunokuphelisa ukungcola, ngelixa ukudinwa kuyanceda ukufumana isisombululo esizinzileyo ngakumbi.

I-3. Izilumkiso
Umgangatho wamanzi kunye nobushushu: Umgangatho wamanzi unefuthe elibalulekileyo ekuphelisweni kwe-HPMC. Kucetyiswa ukuba ufezekise amanzi athambileyo okanye amanzi athambileyo ukuthintela ukuhlaselwa okubangelwa yi-calcium kunye ne-Ignesium i-Ions kumanzi anzima. Iqondo eliphakamileyo kakhulu okanye eliphantsi kakhulu liya kuchaphazela isothulolo kunye nefuthe lokutyibilika kwe-HPMC kwaye kufuneka lilawulwe ngaphakathi kuluhlu olufanelekileyo.

Isantya kunye nexesha: Isantya esiphezulu kakhulu sinokwazisa ngenani elikhulu lomoya kunye neefom zefom; Isantya esisezantsi kakhulu sinokubangela ukudityaniswa okungalinganiyo. Iiparamitha ezivuselelayo kufuneka zilungiswe ngokwezixhobo ezithile kunye nefomula.

Thintela ukungasebenzi: Xa usongeza umgubo we-HPMC, kufuneka kongezwe kancinci kwaye ulunge, kwaye ugcinwe ushukumisa ukuthintela ukwakhiwa kwe-Agglomerates. Umgubo unokuba yinxalenye yamanzi abandayo okanye iarhente yokulwa i-anti-ye-anti-carment inokusetyenziswa.

Ukugcinwa nokusetyenziswa: Isisombululo esilungiselelwe i-HPMC kufuneka sigcinwe kwisitya esivaliweyo ukunqanda ukukhanya kunye nobushushu obuphezulu. Xa igcinwe ixesha elide, isisombululo selizwe kufuneka sihlolwe rhoqo ukuthintela ukutshabalala okanye ukuwohloka.

Ukuxuba i-Hydroxypropyl Methylcelceluplose kufuna ulawulo lwenkqubo engqongqo kwaye inkqubo yokusebenza yokuqinisekisa ukusebenza kunye nefuthe kwimveliso yokugqibela. Ngokuchongwa kwezixhobo ezichanekileyo, ukusetyenziswa kwesinyibilikisi, indlela yokuxuba, indlela yokudibanisa kunye nezisombululo eziphezulu ze-HPMC zinokuzilungiselela ukufezekisa iimfuno zeenkalo ezahlukeneyo zesicelo. Ngokwenyani, uhlengahlengiso kunye nolondolozo kufuneka lwenziwe ngokweemeko ezithile ukufumana isiphumo sokuxuba.