I-HydroxyPOpyl Methylcelcelsulose (HPMC) sisisele esisetyenziswa ngokubanzi kumashishini ahlukeneyo njengamayeza, ukutya nolwakhiwo. Ukusebenza kwayo kunye neepropathi zenza isithako esibalulekileyo, ngakumbi kumzi-mveliso wamachiza apho isetyenziswa khona njenge-Binder, yokumisa iarhente kunye ne-viscomety enyukayo. I-HPMC yaziwa ngokubanzi ngamaza ayo okugcinwa kwamanzi, edlala indima ebalulekileyo kwiintlobo ngeentlobo kunye nezicelo.
Ukugcinwa kwamanzi kukukwazi ukubamba okanye ukugcina amanzi. Kwimeko ye-HPMC, kukukwazi ukufumana amanzi, ngakumbi kwizisombululo ezizeleyo. Ukugcinwa kwamanzi i-HPMC kuyachaphazeleka ngezinto ezininzi, kubandakanya uxinzelelo lwayo, i-viscosity, ubushushu kunye ne-PH.
Enye yezona zinto ziphambili ezichaphazela ukugcinwa kwamanzi i-HPMC kukohlukaniso kwazo. I-HPMC inamanzi aphezulu ogcino lwamanzi kwiindawo eziphezulu. Njengoko uxinzelelo lwe-HPMC, i-viscofity yayo iyanda, ikhokelela ekugcinweni kwamanzi aphezulu. Nangona kunjalo, uxinzelelo kakhulu lunokubangela ukwehla komthamo wokugcina amanzi, oko kuchaphazela intsebenzo iyonke yemveliso.
Enye into echaphazela ukugcinwa kwamanzi kwe-HPMC ngu-Viskosity. UVICWASITY ubhekisa ekuchaseni ukuhamba kwe-HPMC. Ukuphakama okuphezulu, ukuphakama komgangatho wokugcina amanzi. Nangona kunjalo, uVenkile oPhakamileyo unokukhokelela ekuhlanjuleni okungalunganga, okunokuchaphazela kakubi ukusebenza kwemveliso. Ke ngoko, ukulingana okufanelekileyo phakathi kokufakwa kwindawo yokugcina kunye nokuphatha amanzi kufuneka kugcinwe ukuze kufezekiswe iziphumo ozifunayo.
Ubushushu buchaphazela ukugcinwa kwamanzi kwe-HPMC. Kwiqondo lobushushu ephezulu, i-HPMC inomthamo ophantsi wokugcina amanzi. Kungenxa yokuba amaqondo obushushu aphezulu anokubangela ukupheliswa, kubangela ukuba i-HPMC iphulukane namandla ayo ukugcina amanzi. Ngokwahlukileyo, amaqondo obushushu asezantsi akhuthaza ukugcinwa kwamanzi, esenza i-HPMC i-HPMC ilungelo lokufumana isithako esifuna ukugcinwa kwamanzi, njengekhrim kunye neziqwengana.
Ixabiso le-PH yesisombululo likwachaphazela ukugcinwa kwamanzi kwe-HPMC. Ngamanqanaba asezantsi e-PH, i-HPMC inomthamo ophezulu wokugcina amanzi. Kungenxa yokuba iimeko ze-acidic zikhuthaza ukufunxa kwamanzi kwi-HPMC. Kwelinye icala, i-HPMC inamanzi aphantsi okugcina amanzi kwixabiso le-PH. Iimeko ze-alkaline zinokubangela i-HPMC ukuze iphulukane neepropathi zokugcina amanzi, ezikhokelela ekusebenzeni kakubi.
Ukugcinwa kwamanzi i-HPMC yipropathi ephambili echaphazela intsebenzo kunye nokusebenza kwayo kwiimveliso ezahlukeneyo kunye nokusetyenziswa. Ichaphazeleka zizinto ezininzi, kubandakanya uxinzelelo, i-viscosity, ubushushu kunye ne-PH. Ukufezekisa iziphumo ezinqwenelekayo, ibhalansi efanelekileyo kufuneka igcinwe phakathi kwezi zinto. Iipropathi ezihle kakhulu ze-HPMC zenza ukuba kubekho isithako esifanelekileyo kwiimveliso ezahlukeneyo, kubandakanya amayeza, ukutya kunye nezinto zokwakha. Njengoko siqhubeka nokuphonononga izinto zayo kunye nezakhono, i-HPMC kulindeleke ukuba idlale indima ebalulekileyo kumashishini ahlukeneyo, inegalelo kuphuhliso lweemveliso eziphambili eziphezulu.
IXESHA LOKUQALA: FEB-19 ukuya ku-1525