I-HPMC inceda njani ukuphucula ukusebenza kodaka kunye nodaka

I-HydroxyPOpyl Methylcelcelsulose (HPMC) yi-Ionic se-ionic selsulose i-Etely isetyenziswe ngokubanzi kwizinto zokwakha, ngakumbi udaka kunye nodaka. Njenge-SOPITE, i-HPMC inokuphucula kakhulu ubutyebi ohlukeneyo kwezi zixhobo, kubandakanya ukugcinwa, ukugcinwa kwamanzi, ukumelana, njl njl.

1. Iipropathi zeekhemikhali kunye nolwakhiwo lwe-HPMC

I-HPMC yi-polymer ye-semi-synthemetic efunyenwe ngokuguqula amaqela e-hydroxyl kwi-methyred kunye ne-hydroxyypropy. Iyunithi yayo esisiseko ye-Glucose, exhunyiwe yi-β-1,4-Glycosidic Bonds. I-chain ende yeselselose inika ipropati yokwenza ifilimu kunye ne-oneptives, ngelixa ukumiliselwa kwe-methyl kunye namaqela e-hydroxlypropyl kuphucula ulwalamano lwayo kunye nozinzo.

Isakhiwo sekhemikhali se-HPMC sinika ezi mpawu zilandelayo:

I-Solubaty yaManzi: inokuchitha ngokukhawuleza emanzini ebandayo ukwenza i-viscous i-viscous flousis.

Uhlengahlengiso lwe-Viscosity: Isisombululo se-HPMC sinophawu olusebenzayo, oluxhomekeke kubunzima bemolekyuli kunye noxinzelelo.

Uzinzo: Kuzinzile kwii-acids kunye neziseko kwaye unokugcina intsebenzo yayo ngaphezulu kwe-PH.

2. Iindlela ze-HPMC ukuphucula ukusebenza kodaka kunye nodaka

(2.1). Ukuphucula ukugcinwa kwamanzi
Ukugcinwa kwamanzi kubhekisa kubuchule bodaka okanye i-Plaster ukugcina amanzi, ebaluleke kakhulu kwi-shydrations hydration kunye nenkqubo yokuqinisa. I-HPMC iphucula ukugcinwa kwamanzi ngezi ndlela zilandelayo:

Ukuqulunqwa kwefilimu: I-HPMC yeyona filimu emdaka kwifilimu okanye i-Plaster, inciphise iqondo lokuphuma kwamanzi.
I-MALECAN YOKUGQIBELA: Imolekyuli ze-HPMC inokufunxa isixa esikhulu samanzi, ukunciphisa ukulahleka kwamanzi ngexesha lokwakha.
Ukugcinwa kwamanzi aphezulu kunceda isamente eqatha ngokupheleleyo, ngaloo nto iphucula amandla kunye nezinto ezibonisa ubutshijolo kunye nodaka. Ukongeza, ikwanciphisa ukwakhiwa kwemingxunya ebangelwe kukulahleka kwamanzi kakhulu.

(2.2). Ukuphucula ukusebenza
Ukusebenza kubhekisa kwintsebenzo yokusebenza kodaka kunye nodaka ngexesha lenkqubo yokwakha, njengolwelo kunye nokusebenza. Iindlela apho i-HPMC iphucula khona ukusebenza ukuba ibandakanya:

Ukuphucula iplasitiki: i-HPMC ibonelela nge-conbrity elungileyo, inika iprintration engcono kunye nolwelo.
Ukuthintela ukulibaziseka kunye nokwahlulahlula-hlula: Iziphumo ezihlekisayo ze-HPMC zinceda ekusasazeni amasuntswana, ukuthintela ukuqondiswa okanye indawo yokuvala kodaka.
Oku kwenza ukuba udaka okanye udaka kube lula ukuba lusebenze nangemva kokwakhiwa, ukuvumela ukusetyenziswa nokusetyenziswa okuninzi kunye nokuzonwabisa, ukunciphisa ukubakho kwenkunkuma kunye nokuhlawula.

(2.3). Ukonyuka kokunganyangeki kokuqhekeka
Udaka kunye nodaka lunokuqhekeka ngenxa yokuncitshiswa kwevolumu ngexesha lokuqina, kwaye i-HPMC iyanceda ukunciphisa le nto:

Ukuguquguquka: Isakhiwo senethiwekhi ezenziwe yi-HPMC kwi-Sunin yonyusa ukuguquguquka kodaka kunye nodaka, ngalopho ukufunxa koxinzelelo kunye nokukhulula uxinzelelo.
I-iyunifomu yomile: kuba i-HPMC ibonelela ngokugcinwa kwamanzi kakuhle, amanzi anokukhutshwa ngokulinganayo, ukunciphisa utshintsho lwevolumu ngexesha lomomo.
Ezi ndawo zinciphisa ukubakho kokumiliselwa kwe-rack kunye nokuphucula ukuqina kwento leyo.

3. Imizekelo yezicelo ze-HPMC kumdaka kunye nodaka

(3.1). I-TIILE AYIDE
ETile Abenoive, i-HPMC ibonelela ngogcino lwamanzi afanelekileyo kunye ne-anti-slip, ivumela iithayile zokulandela i-suts kwi-substrate kwi-substrate kwaye igcine ulwakhiwo olusebenzayo lokwakha.

(3.2). Ukuthathwa kwenqanaba lokuzimela
Ukuthathwa kokuzihlisa kufuna ulwelo oluphezulu kunye neepropathi zokuzimela. Ukugcinwa kwamanzi aphezulu kunye nokugcinwa kohlengahlengiso lwe-HPMC kunye nokuQeqwa kwe-viscosity Pobletions uncedo kufezekisa ezi mfuno, kukhokelela kwindawo egudileyo.

(3.3). Udaka
I-HPMC inyusa ubunamatheko kunye nokunganyangeki kodaka, ngakumbi kulawulo lwangaphandle lwangaphandle, kwaye kunokumelana ne-racker kwaye iwele ebangelwa zizinto ezahlukeneyo zokusingqongileyo.

I-4. Izilumkiso zokusetyenziswa kwe-HPMC

(4.1). Ukusetyenziswa
Isixa se-HPMC esisetyenziselwa i-HPMC kunye nodaka sihlala siyimali encinci ngokwepesenti ubunzima, njenge-0.1% ukuya kwi-0.5%. I-HPMC eninzi iya kukhokelela ekuvenisweni kakhulu kwaye kuchaphazele ukusebenza; Kancinci kakhulu kuya kwenza ukuba kube nzima ukuphucula intsebenzo.

(4.2). Ukuhambelana nezinye izongezelelo
Xa usebenzisa i-HPMC, kuyimfuneko ukuqwalaselwa kokuhambelana nezinye iikhemikhali (ezinjengamanzi, iiarhente zokungena zomoya, njl. Njl.) Ukuqinisekisa ukuba akukho ntshukumo imbi yekhemikhali okanye ukusebenza kwesixhobo esichaphazelekayo.

Njengophawu olubalulekileyo lweekhemikhali, ukusetyenziswa kwe-HPMC kumdaka kunye nodaka luphuluke kakhulu ukugcinwa kwamanzi, ukusebenza kunye nokunganyangeki. Olu phuculo aluphumi nje ukwenza umphumo wokwakha kunye nomgangatho wezinto, kodwa kukuphucula ukuqina kunye nokuthembeka kweprojekthi. Kwizicelo ezithile, ngokuhlengahlengiswa ngokuvakalayo umthamo kunye nomyinge we-HPMC, ukusebenza kodaka kunye nodaka kunokuphumelela ngokufanelekileyo.