I-Hydroxypropyl Methylcelcelsulose (HPMC) i-selsulose eqhelekileyo (i-HPMC) isuswe ngokubanzi kwiimveliso zokucoca, ikakhulu zisetyenziselwa ukuhlengahlengisa i-viscofity, uzinzo kunye neengqolowa zemveliso. Ngemfuno eyandayo yabathengi kwiimveliso zokucoca ezifanelekileyo kunye nezendalo, indima ye-HPMC kwi-viscosity yolawulo iyaqhubeka ngakumbi kwaye ibaluleke ngakumbi. Nangona kunjalo, indlela yokuphucula ngokufanelekileyo ukulawulwa kwe-viscofity ye-HPMC kwiimveliso zokucoca kunye nokwenza umsebenzi wemveliso kusesisihloko esifanelwe kukufunda okunzulu.
(1) Iimpawu ezisisiseko ze-HPMC
I-HPMC yi-Infor-aillic foll setesulose i-ether enamanzi amnandi, ukwenziwa kwefilimu, ukumiswa kwefilimu kunye nemisebenzi yezinto. Isakhiwo sayo semolekyuli siqukethe i-hydroxylypropy kunye namaqela e-methyl, enika amandla ngokufanelekileyo kunye nozinzo. Emva kokuba i-HPMC inyibilikisa emanzini, iyenza isisombululo esibonakalayo seColoidal, esinokuthi sandomeleza ngokufanelekileyo i-viscofity yenkqubo yolwelo kwaye kuthintele i-suciplessubles eqinileyo, ngaloo ndlela idlala indima yoqhelaniso.
Kwiimveliso zokucoca, i-HPMC isetyenziswa ikakhulu njenge-thickener kunye nomlawuli we-viscosity. Inganika iimveliso zokucoca ezifanelekileyo zezahlulo ze-rothological, ukuze zibethendezelweni okuhle kwaye zibuthathaka ngexesha lokusetyenziswa. Ukongeza, i-HPMC inamatyala omeleleyo kunye nokuzinza kweqondo lobushushu, kwaye ilungele iintlobo ngeentlobo zemveliso yokucoca, ezinje ngezicotho, ii-sashitizers zesandla, i-shamps, njl.
(2) Imeko yesicelo ye-HPMC kwiimveliso zokucoca
Isiphumo sokuqaqamba: I-HPMC yenziwa inethiwekhi yenethiwekhi ye-hydrogen ye-hydrogen ye-qhydrogen kwinqanaba le-ACHEDROGINS lokwandisa ukumiswa kwesisombululo, ukwenza ukuba imveliso yokucoca ineemvakalelo ezimbalwa kwaye uzinzo. Umzekelo, kwizitolo, i-HPMC inokuphucula ngokufanelekileyo ukungangqinelani kwemveliso ukuthintela ukuba mncinci kakhulu kwaye ichaphazela isiphumo sokucoca. Kwangelo xesha, inokuphucula ukusasazeka kwe-creagent kwaye yenze ireyithi yayo yokuchitheka emanzini ngaphezulu.
Ulawulo lwe-ROOILOC: I-HPMC inokuhlengahlengisa iipropathi ze-RIOOOOOOLOTER yeemveliso zokucoca, oko kukuthi, ukuhamba nokuhamba kwengcaciso yemveliso phantsi kweemeko ezahlukeneyo. Iipropathi zeRheelogic efanelekileyo ayichaphazeli amava omsebenzisi wemveliso, kodwa ikwachaphazela uzinzo lwemveliso ngexesha lokugcina. Umzekelo, i-HPMC inokugcina i-wititizer yesandla kwi-viscofity efanelekileyo kumaqondo obushushu asezantsi ukunqanda ukuba angabi mncinci okanye ahlukane.
Ukunqunyanyiswa kunye nokuzinzisa okuzinzileyo: kwiimveliso zokucoca ezinamasuntswana aqinileyo, i-HPMC inokuthintela ngokufanelekileyo amasuntswana anokuhlala kwaye aqinisekise ngokufanayo kwemveliso ngexesha lokugcina ixesha elide. Umzekelo, iziciko zinokuba nee-amosis okanye intsholongwane. I-HPMC inyusa i-viscofity yenkqubo yokuqinisekisa ukuba la masuntswana aqingqiweyo anqunyanyisiwe kulwelo kwaye uthintele ekusombululeni ezantsi kwibhotile.
(3) Imiceli mngeni kulawulo lwe-HPMC Viscosity
Nangona i-HPMC inezibonelelo ezibalulekileyo kulawulo lwe-viscofity, kusekho imiceli mngeni kwizicelo ezenziwayo, ikakhulu kwezi zinto zilandelayo:
Isiphumo sobushushu obahlukeneyo kwi-viscosity: i-HPMC inovelwano ngamaqondo obushushu, kwaye ukubonwa kwayo kuya kuncitshiswa kakhulu kubushushu obuphezulu, onokukhokelela ekunciphiseni kwemveliso kwezinye izinto zesicelo. Umzekelo, kwinqanaba lobushushu obuphezulu ehlotyeni, ukungqinelana kwesicocimi kunokuncipha, kuchaphazela ukusebenza ukusetyenziswa.
Isiphumo samandla e-Ionic kwi-vickosity: Nangona i-HPMC inomthi othile, isiphumo esihle se-HPMC sinokwenza buthathaka phantsi kweemveliso ezinkulu ze-Ionic, njengokuhlamba umgubo kunye nokuchithela kweenyawo. Kule meko, ubuchule bokuthathwa kwe-HPMC kuya kuthintelwa, zenze kube nzima ukugcina i-velomosity yemveliso.
Utshintsho lwe-viscosity ngexesha lokugcina ixesha elide: Ngexesha lokugcina ixesha elide, i-viscosity ye-HPMC inokutshintsha, ngakumbi phantsi kweemeko zeqondo lobushushu obukhulu kunye nokuguquguquka komsindo omkhulu kunye nokuguquguquka komsindo omkhulu kunye nokuqhawuka komswakazi omkhulu kunye nokufana. Utshintsho kwi-vickosity kunokukhokelela ekunciphiseni uzinzo lwemveliso kwaye kuchaphazele isiphumo sayo sokucoca kunye namava abasebenzisi.
(4) Izicwangciso zokuphucula ukulawulwa kwe-viscofity ye-HPMC
Ukwenzela ukuphucula ulawulo lwe-HPMC kwiimveliso zokucoca, amanyathelo ahlukeneyo anokuthathwa, ekufezekiseni ubume bemolekyuli ye-HPMC ukuhlengahlengisa ezinye izithako kwifomula.
1. Ukulungiselela ubume bemolekyuli ye-HPMC
Uhlobo lwe-HPMC luhambelana ngokusondeleyo nobunzima bemolekyuli kunye nenqanaba lokufaka endaweni (inqanaba lokufakwa endaweni ye-methyl kunye namaqela e-hydroxypropy). Ngokukhetha i-HPMC kunye nee-moleks zemolekyuli ezahlukeneyo kunye nezigameko zokufakwa endaweni, isiphumo sayo sokuthambisa kwiimveliso ezahlukeneyo zokucoca zingahlengahlengiswa. Umzekelo, ukukhetha i-HPMC enenqanaba elikhulu lemolekyuli inokuphucula uzinzo lwayo lobushushu, olufanelekileyo kwiimveliso zokucoca ehlotyeni okanye kwindawo yobushushu obuphezulu. Ukongeza, ngokuhlengahlengisa inqanaba lokufaka endaweni, ukumelana netyuwa kwe-HPMC kunokuphuculwa, ukuze igcine i-viscofity elungileyo kwiimveliso eziqukethe ii-elektroniki.
2. Sebenzisa inkqubo yokuthambisa
Kwizicelo ezisebenzayo, i-HPMC inokuqulunqwa kwezinye iziqwengana zokuphucula isiphumo sayo sozinzo kunye nozinzo. Umzekelo, usebenzisa i-HPMC kunye nezinye iziqwengana ezinjengeXanthan Gum kunye nekhadbhombu inokufezekisa iziphumo ezingcono, kwaye le nkqubo yengqokelela inokubonisa uzinzo kubushushu obahlukeneyo, i-PHSINGORS kunye namandla e-PH.
3. Ukongeza i-solsibizers okanye izilo
Ngamanye amaxesha, ukubenzela amandla kunye nokuzinza kwe-HPMC kungaphuculwa ngokongeza i-solkubers okanye izilongile kwifomula. Umzekelo, ukongeza i-surfacapes okanye i-solbobizers inokuphucula inqanaba lokuchitheka kwe-HPMC emanzini, ivumela ukuba idlale indima enkulu ngokukhawuleza. Ukongeza, ukongeza ii-stabilizers ezinje nge-ethanol okanye i-orresvatives kunokunciphisa ukonakaliswa kwe-HPMC ngexesha lokugcina kunye nokugcina uzinzo lwexesha elide.
4. Lawula indawo yokuvelisa kunye nendawo yokugcina
I-viscosity ye-HPMC inovelwano kubushushu kunye nokufuma, iimeko zokusingqongileyo kufuneka zilawulwe kangangoko kunokwenzeka ngexesha lokuvelisa kunye nokugcina. Umzekelo, ngexesha lenkqubo yokuvelisa, ngokulawula ubushushu kunye nokufuma, unokuqinisekiswa ukuba i-HPMC i-SPMC i-tickens kunye neebhulukhwe phantsi kweemeko ezifanelekileyo zokuthintela imicimbi yendalo. Ngexesha lokugcina, ngakumbi kumaxesha obushushu aphezulu, imveliso kufuneka ithintelwe ekubeni ivezwe kwiindawo ezixineneyo ukuthintela utshintsho kwimveliso.
I-5. Ukuphuhlisa i-HPMC entsha
Ngokutshintsha imichiza i-HPMC MOLECOLE kunye nokuphuhlisa izaphulelo ezintsha ze-HPMC, intsebenzo ye-viscomity yolawulo lwe-Viscofity inokuphucuka ngakumbi. Umzekelo, ukuphuhlisa i-HPMC ye-HPMC enobushushu obunobushushu obunamandla kunye nokuxhathisa i-electrolyte kunokuhlangabezana kakuhle neemfuno zefomu yokucoca ezintsonkothileyo. Ukongeza, ukuphuculwa kweemveliso ze-HPMC zendalo kunye ne-biodegrady HPMC kuya kunceda ukuphucula ukusebenza kwendalo yeemveliso zokucoca kwaye kulandele imeko yangoku ye-chemistry ye-chemistry yeGreen.
Njengomlawuli obalulekileyo we-tickener kunye nomlawuli we-viscosity, i-HPMC inamachaphaza asetyenzisiweyo asetyenzisiweyo kwiimveliso zokucoca. Nangona kunjalo, ngenxa yobuntununtunu kwimiba yendalo esingqongileyo efana nobushushu kunye namandla e-Ionic, imiceli mngeni kulawulo lwe-HPMC Viscosity likhona. Ngokwenza into eqinisekileyo ye-HPMC, isebenzisa inkqubo yokuthambisa, yongeza i-slolwobizers okanye izizwe, kunye nokulawula imeko yokusebenza kwe-HPMC kwiimveliso zokucoca kunokuphuculwa ngokufanelekileyo. Kwangelo xesha, ngokuphuhliswa kwe-HPMC entsha, uLawulo lwe-viscosity lweemveliso zokucoca kwixesha elizayo luya kuba luncedo ngakumbi kwaye luzinzile, ukuphucula ukusebenza kweemveliso zokucoca kunye nemveliso yomsebenzisi weemveliso zokucoca.
IXESHA LOKUQALA: NgoFebruwari-17-2025