Ngaba i-HPMC inganyibilika emanzini ashushu?

I-HPMC (Hydroxypropyl Methylcelcelcelose) i-selsulose esetyenziswa ngamanzi asetyenziswayo, esetyenziswa ngokubanzi ekwakhiweni, impahla, amayeza, ukutya kunye namanye amashishini. Ifunyanwa ngokutshintsha kwekhemikhali ye-selupose yendalo. Iimpawu zayo zesakhiwo zikwenza ukuba kube senze isisombululo se-viscofity ephezulu kwaye sibe nomoya othile.

Ngaba i-HPMC inganyibilika emanzini ashushu?
I-HPMC inokupheliswa ngamanzi ashushu, kodwa inkqubo yayo yokuchithelwa kwayo inxulumene nemeko efana neqondo lobushushu, amaqondo obushushu amanzi okupheliswa, ubunzima be-phumc, kunye nenqanaba lokuguqulwa. Ngokubanzi, i-HPMC inokunyibilika kubushushu begumbi, kodwa izinga lokuchithwa ziya kukhawuleza kumaqondo obushushu aphezulu.

1. Indlela yokuphelisa
Indlela yokunyibilikisa ye-HPMC ixhomekeke ikakhulu kwi-hydrophicicity ye-hydroxyl kunye namaqela e-methyl kunye namaqela e-propyl nakwiimolekyuli zayo. Iimolekyuli zamanzi zinokusebenzisana ne-Hydroxyl kunye namaqela e-HETYL kwiimolekyuli ze-HPMC ngebhondi ye-hydrogen, ukuze imixokelelwane yeselula ingenziwa kwaye ekugqibeleni isisombululo esingempela senziwa. Ke ngoko, i-HPMC inomoya ofanelekileyo wamanzi.

2. Isiphumo seqondo lokushisa i-swecing kwi-sloubing ye-HPMC
Ukunyibilika kwe-HPMC kuhlala kunyuka ngokukhulisa ubushushu obukhulayo. Phantsi kweemeko zobushushu obuphezulu, amandla e-kinetic onyukayo eemolekyuli zamanzi ayanda, kwaye banokunxibelelana ngempumelelo namaqela e-hppmcilic kwiimolekyuli ze-HPMC, ngaloo ndlela ukukhawulezisa inkqubo yabo yokuchitheka. Ingakumbi i-HPMC kunye nobunzima obuphakathi, amanzi ashushu anokukunceda ukuba inyibilike ngokukhawuleza.

Nangona kunjalo, i-sloubing ye-HPMC ayixhomekeki kubushushu, kodwa nakwindlela yayo yotshintsho. Imilinganiselo eyahlukeneyo yeqela lekhemikhali kwi-HPMC Mulekcule ichaphazela ukonakala kwamanzi kunye nenqanaba lokuchitha. Umzekelo, i-HPMC ene-hydroxdpropy ye-hydropyl ye-hydropypropy ine-hydrophility kwaye ke inyibilike ngokukhawuleza emanzini.

3. Isiphumo seqondo lobushushu obuphezulu kwixabiso lokuchitha
Kumaqondo obushushu aphezulu, inqanaba lokuchitha i-HPMC liya kukhawuleziswa kakhulu. Ngokukodwa, kuluhlu lwama-60 ° ukuya kwi-90 ° C, ireyithi ye-HPMC iphuculwe kakhulu. Kungenxa yokuba amanzi ashushu anokutshabalalisa ngempumelelo iimolethi ze-hydrogen phakathi kweemolekyuli, avumela iimolekyuli zamanzi ukuba zingene kwi-molecular ye-MEPMC ngokukhawuleza, ngaloo ndlela ikhuthaza ukutshitshiswa kwayo.

I-4. Iingxaki ezinokuthi zihlanganyenwe ngexesha lokupheliswa
Nangona i-HPMC inokuchithwa emanzini ashushu, ukuba iqondo lobushushu liphezulu kakhulu, i-HPMC kwisisombululo inokwenza ukonakala okanye utshintsho oluyindlela, ngakumbi xa liboniswe kubushushu obuphezulu ixesha elide. Oku kunokuchaphazela ukubonakala kwayo kunye nomsebenzi, ngakumbi kwezinye iindawo zesicelo, olu tshintsho lunokuba nefuthe kumgangatho wemveliso yokugqibela.

Ukuba iqondo lobushushu lamanzi elongezwe ngexesha lenkqubo yokupheliswa iphezulu kakhulu, i-HPMC POLMDER inokwenza i-sublomeramed emanzini, ikhokelela ekuchitheni okungapheliyo. Ke ngoko, ukwenzela ukutshitshiswa ngokupheleleyo kwe-HPMC, ihlala icetyiswa ukuba isebenzise amanzi afudumeleyo ngexesha lokupheliswa kunye nokwamkela iindlela ezifanelekileyo zokuvuselela okanye i-ultrasonic encedisayo.

Imizekelo yomzekelo wokuchithwa kwamanzi ashushu kwi-HPMC
Kwizicelo ezisebenzayo, ukuvela kwamanzi okushushu kwe-HPMC kuhlala kusetyenziswa. Umzekelo, kumzi-mveliso wokwakha, i-HPMC, njengomntu obalulekileyo, unokubonelela nge-gemology egqwesileyo, ukunamathela kunye nokugcinwa kwamanzi ngokusabela ngamanzi. Xa ulungiselela isamente yesamente okanye i-HPMC, i-HPMC inokunceda ukuphucula ukusebenza nokuthintela ukuqhekeka.

Kumzi-mveliso wamayeza, i-HPMC isetyenziswa ngokubanzi ekwenziweni kweearhente zokukhutshwa ezizinzileyo kunye ne-capsule ye-capsule yeziyobisi. Ngenxa yomoya wayo olungileyo, i-HPMC inokuphefumla kancinci emzimbeni womntu kwaye ikhuphe izithako zamachiza. Kule nkqubo, iqondo lobushushu lamanzi kunye nereyithi yokuchithwa kwe-HPMC idlala indima ebalulekileyo.

Kwishishini lokutya, i-HPMC, njengesongezo lokutya, ihlala isetyenziswa njengendawo enkulu, i-enulsifier, njl. Njl.

I-HPMC inokuchithwa emanzini ashushu, kwaye ukuluka kwayo kunxulumene nobushushu bamanzi, isakhiwo semolekyuli se-HPMC, ubunzima bemolekyuli kunye nokuguqulwa kwemichiza. Kwiqondo lobushushu ephezulu, ireyithi yokuchithwa ikhawuleza, ihlala ikwinqanaba lama-60 ° C ukuya kwi-90 ° C, isiphene sesondlo. Xa usebenzisa amanzi ashushu ukunyibilikisa i-HPMC, kunyanzelekile ukuba unikele ingqalelo ekunikezeleni ubushushu bamanzi kunye nexesha lokuphelisa ifuthe elibi leqondo lobushushu eliphezulu ekusebenzeni kakhulu.