Izinto eziluncedo kwi-hydroxypropy ye-hydropyl ye-hydroplopy kwiZicelo zeZicelo zeMachis

I-hydroxypropyl ye-hydroplopyl ye-hydulose ye-hydulose (HS-HPC) inomdla onezinto ezibalulekileyo kwintsimi yamayeza. Ngenxa yepropathi yayo eyahlukileyo kunye nezamzimba, idlala indima ebalulekileyo kwimisebenzi yamayeza.

I-1. Ukungasebenzi kunye nokuzola kwamanzi
I-Solity elawulwa
I-hydroxypropy ye-hydroplopy ye-hydroplopy ye-hydroplopy ye-hydulose inesifo esihle emanzini kwaye inokukhawuleza inyibilike ukuze ibe sisisombululo se-viscofity ephezulu. Le profayile ye-Solboubing iyenza ilungele ukulungiswa kwefomuli ye-Oral, izixhobo, kunye nezicelo ezizicebisi. Kwimisebenzi yeziyobisi, inqanaba lokuchithwa kwe-HS-HPC lingalawulwa ngokuhlengahlengiswa kwenqanaba lokufakwa endaweni ye-HydroxyPlPlIt yamaqela okufezekisa iimfuno ezahlukeneyo zokukhululwa kweziyobisi.

Isiphumo seSolboubIling
I-HS-HPC inokonyusa isotha yamachiza athile e-hydrophobic, ngaloo ndlela ukuphuculwa kwebhayoloji yeziyobisi. Oku kubaluleke ngakumbi kwezo iziyobisi zinyibilikayo, ezinokuphucula ukubenzela isolula kunye nokuthathwa ngokuqulatha izinto ezinyibilikayo zamanzi.

I-2. Uhlengahlengiso lwe-viscosity kunye neepropathi ze-rheoology
Ulungelelwaniso lwe-viscosity
I-HS-HPC ikwazile ukwenza izisombululo ze-vicous kakhulu emanzini, ipropathi eyenza ukuba isetyenziswe njengendawo yokuziqhelanisa nokuzimisa. Umzekelo, kuminyeliso lomlomo, inokuthintela ngokufanelekileyo amasuntswana aqinileyo anokuhlala, aqinisekise ukusasazwa kwamachiza, kunye nokuphucula amayeza kanyango.

Uhlengahlengiso lwe-RheOology
Isisombululo se-HS-HPC sine-pseudeoplastity, oko kukuthi, i-viscofity iya kunciphisa phantsi kwesenzo samandla eShear. Le ndawo ibaluleke kakhulu kwizinto ezingenantsingiselo kuba inciphisa ukumelana ngexeshana nenaliti kwaye iphucule intuthuzelo yezigulana.

I-3. Ukuqulunqwa kweefilimu kunye ne-adherions
Ifilimu yefilimu
Iipropathi zokwenza ifilimu ze-HS-HPC yenza ukuba isetyenziswe ngokubanzi kwimveliso yefilimu ekhutshelweyo. Ingayikha i-filimu kunye nefilimu yokuzinza ukunceda ukulawula izinga lokukhutshwa kweziyobisi kunye nokuphucula ukusebenza kweziyobisi. Le ndawo ibaluleke ngokukodwa kwiitafile zomlomo ezandisiweyo kunye neecapbules, ezinokwandiswa kakhulu ixesha lesenzo kunye nokunciphisa i-frequency yedosi.

Iipropathi zomnyango
Iipropathi ezintle zokunamathela ze-HS-HPC zenza ukuba ilungele amalungiselelo e-mucosal. Umzekelo, kwiifilimu zomlomo kunye namalungiselelo okukhutshwa kwe-mucosal, i-HS-HPC inokubalandela ngokufanelekileyo kumgangatho we-MUCOSAL ukuqinisekisa ukukhutshwa kwendawo kunye nokuthathwa kwechiza.

4. Uzinzo kunye ne-bicomatise
uzinzo lweekhemikhali
I-HS-HPC inozinzo ezigqwesileyo zekhemikhali, ihlala izinzile ngaphezulu kwe-PH ye-PH, kwaye ayihambelani kwi-hydrolysis okanye ukonakala. Olu qini luyenza ukuba ikwazi ukuhlala isebenza ngeendlela ezahlukeneyo zamachiza, ukuqinisekisa uzinzo lwexesha elide kunye nokhuseleko lwechiza.

Ukucofa
I-HS-HPC ine-biomatining elungileyo kwaye inokuthi ihambelane nezicubu zomzimba kunye nolwelo lomzimba ngaphandle kokuzibamba okanye ukucaphukisa. Oku kwenza ukuba i-HS-HPC isetyenziswe ngokubanzi amalungiselelo ngamayeza ngamayeza, ngakumbi kumachiza e-Ophthalmic kunye nenaliti, ukuqinisekisa ukhuseleko kunye nokusebenza kwamachiza.

5. Qhubeka nokuziqhelanisa nokuzonwabisa
QAPHELA UKUZIPHATHA
I-HS-HPC ilungele iinkqubo ezahlukeneyo zokuqunjelwa, kubandakanya ukutshiza okumangalisayo, ukunyibilika okumanzi kunye nokunyibilika. Inkqubo yayo elungileyo yokuziqhelanisa nendlela yokuziqhelanisa neyokwenza ukuba isetyenziswe ngokuguquguquka kwiinkqubo zamachiza, iphucule ukusebenza kakuhle nokunciphisa iindleko.

Uqwalaselo
I-HS-HPC ibalulekile njengokuthanda amayeza. Ayinakusetyenziswa kuphela njenge-binder kunye ne-tickener, kodwa i-arhente yefilimu yefilimu kunye ne-stabilizer. Oku kuqalisa ukusebenza kwenza ukuba i-HS-HPC isebenze kwiindlela ezahlukeneyo zokwenziwa kwamayeza, ukwenziwa kokuqulunqwa kokuqulunqwa kunye nokuphucula ukusebenza kwemveliso.

I-6. Umsebenzi wokukhutshwa olawulwa kunye nommiselo wokukhutshwa kweziyobisi
Iipropati ezilawulwayo
I-HS-HPC inokufezekisa ukukhutshwa kwamachiza okulawulwa ngokuqulunqa inethiwekhi edibeneyo okanye enze ubunzima ngamachiza. Le ntlawulo ilawulwa ilawulwa ibaluleke ngokukodwa kwiitafile ezikhuselekileyo zokukhutshwa kunye ne-capsules, ezinokwandisa kakhulu ixesha lokwenza iziyobisi kunye nokuphucula ukuthotyelwa komonde.

Ummiselo wokukhutshwa kweziyobisi
Ngokuhlengahlengisa ubunzima bemolekyuli, isidanga sokufakwa endaweni, kunye nokususwa kwe-HS-HPC, inqanaba lokukhutshwa ngamachiza linokulawulwa ngokuchanekileyo. Obu buchule bokulawula ukukhutshwa kweziyobisi kwenza ukuba iinjineli zamayeza zokuyila iifomu zokunxibelelana neziyobisi ezihlangabezana nezidingo ezikhethekileyo zonyango kunye nokuphucula ukusebenza kweziyobisi.

I-7. Ubuhlobo bokusingqongileyo kunye nokudakumba
I-HS-HPC isuselwa kwi-seluplose yendalo kwaye inesixhobo esihle se-biode kunye nobuntu bokusingqongileyo. Ingaphuhliswa ziintsholongwane kwizinto ezingenabungozi ngaphakathi nangaphandle komzimba, ezihlangabezana neemfuno zeyeza eziluhlaza zamayeza eziluhlaza kwaye zinciphisa umngcipheko wokungcoliseka kwendalo.

I-hydroxypropy ye-hydroplopy ye-hydroplopy ye-hydroplopy ineenzuzo ezibalulekileyo kwizicelo zamayeza, kubandakanya ukuzomalala okuhle, uhlengahlengiso lwefilimu, uhlengahlengiso lwefilimu, ukusetyenziswa kwenkqubo yokusebenza, ukunxibelelana okusingqongileyo. Ezi mpawu zenza i-HS-HPC i-Indiabiant inomdla kumzi-mveliso wamachiza, ukubonelela ngenkxaso eqinileyo kuphuhliso lwamayeza asebenza ngokufanelekileyo, akhuselekileyo, ahlala ngokuzinza.